Validation of glypican-3-specific scFv isolated from paired display/secretory yeast display library

BACKGROUND: Glypican-3 (GPC3) is a heparan-sulfate proteoglycan frequently expressed on the cell membrane of malignant hepatocytes in hepatocellular carcinoma. The capacity for screening potential antibodies in vitro using human hepatocellular lines is critical to ensure binding to this highly post-...

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Detalles Bibliográficos
Autores principales: Li, Yonghai, Siegel, Donald L, Scholler, Nathalie, Kaplan, David E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3425314/
https://www.ncbi.nlm.nih.gov/pubmed/22564378
http://dx.doi.org/10.1186/1472-6750-12-23

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3425314/
https://www.ncbi.nlm.nih.gov/pubmed/22564378
http://dx.doi.org/10.1186/1472-6750-12-23

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