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Validation of glypican-3-specific scFv isolated from paired display/secretory yeast display library
BACKGROUND: Glypican-3 (GPC3) is a heparan-sulfate proteoglycan frequently expressed on the cell membrane of malignant hepatocytes in hepatocellular carcinoma. The capacity for screening potential antibodies in vitro using human hepatocellular lines is critical to ensure binding to this highly post-...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2012
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3425314/ https://www.ncbi.nlm.nih.gov/pubmed/22564378 http://dx.doi.org/10.1186/1472-6750-12-23 |