EGF and HB-EGF enhance the proliferation of programmable cells of monocytic origin (PCMO) through activation of MEK/ERK signaling and improve differentiation of PCMO-derived hepatocyte-like cells

BACKGROUND: Hepatocyte-like cells (NeoHepatocytes) generated from a peripheral blood monocyte-derived stem cell-like cell (the PCMO) are a promising alternative for primary hepatocytes in cell transplantation studies to cure liver diseases. However, to be therapeutically effective NeoHepatocytes are...

Descripción completa

Detalles Bibliográficos
Autores principales: Hyder, Ayman, Ehnert, Sabrina, Hinz, Hebke, Nüssler, Andreas K, Fändrich, Fred, Ungefroren, Hendrik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3425323/
https://www.ncbi.nlm.nih.gov/pubmed/22873932
http://dx.doi.org/10.1186/1478-811X-10-23

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3425323/
https://www.ncbi.nlm.nih.gov/pubmed/22873932
http://dx.doi.org/10.1186/1478-811X-10-23

Ejemplares similares