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EGF and HB-EGF enhance the proliferation of programmable cells of monocytic origin (PCMO) through activation of MEK/ERK signaling and improve differentiation of PCMO-derived hepatocyte-like cells

BACKGROUND: Hepatocyte-like cells (NeoHepatocytes) generated from a peripheral blood monocyte-derived stem cell-like cell (the PCMO) are a promising alternative for primary hepatocytes in cell transplantation studies to cure liver diseases. However, to be therapeutically effective NeoHepatocytes are...

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Detalles Bibliográficos
Autores principales:	Hyder, Ayman, Ehnert, Sabrina, Hinz, Hebke, Nüssler, Andreas K, Fändrich, Fred, Ungefroren, Hendrik
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2012
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3425323/ https://www.ncbi.nlm.nih.gov/pubmed/22873932 http://dx.doi.org/10.1186/1478-811X-10-23

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