Glypican-4 Enhances Insulin Signaling via Interaction With the Insulin Receptor and Serves as a Novel Adipokine

Obesity, especially visceral obesity, is associated with insulin resistance and metabolic syndrome. We previously identified the cell surface proteoglycan glypican-4 as differentially expressed in subcutaneous versus visceral white fat depots. Here we show that glypican-4 is released from cells and...

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Detalles Bibliográficos
Autores principales: Ussar, Siegfried, Bezy, Olivier, Blüher, Matthias, Kahn, C. Ronald
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2012
Materias:
Signal Transduction
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3425403/
https://www.ncbi.nlm.nih.gov/pubmed/22751693
http://dx.doi.org/10.2337/db11-1395

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3425403/
https://www.ncbi.nlm.nih.gov/pubmed/22751693
http://dx.doi.org/10.2337/db11-1395

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