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Adipocytes Secrete Leukotrienes: Contribution to Obesity-Associated Inflammation and Insulin Resistance in Mice

Leukotrienes (LTs) are potent proinflammatory mediators, and many important aspects of innate and adaptive immune responses are regulated by LTs. Key members of the LT synthesis pathway are overexpressed in adipose tissue (AT) during obesity, resulting in increased LT levels in this tissue. We obser...

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Detalles Bibliográficos
Autores principales: Mothe-Satney, Isabelle, Filloux, Chantal, Amghar, Hind, Pons, Catherine, Bourlier, Virginie, Galitzky, Jean, Grimaldi, Paul A., Féral, Chloé C., Bouloumié, Anne, Van Obberghen, Emmanuel, Neels, Jaap G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3425405/
https://www.ncbi.nlm.nih.gov/pubmed/22688342
http://dx.doi.org/10.2337/db11-1455