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Insulin-Like Growth Factor Axis and Risk of Type 2 Diabetes in Women

IGF-I shares structural homology and in vitro metabolic activity with insulin. Laboratory models suggest that IGF-I and its binding proteins IGFBP-1 and IGFBP-2 have potentially beneficial effects on diabetes risk, whereas IGFBP-3 may have adverse effects. We therefore conducted a prospective nested...

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Detalles Bibliográficos
Autores principales: Rajpathak, Swapnil N., He, Meian, Sun, Qi, Kaplan, Robert C., Muzumdar, Radhika, Rohan, Thomas E., Gunter, Marc J., Pollak, Michael, Kim, Mimi, Pessin, Jeffrey E., Beasley, Jeannette, Wylie-Rosett, Judith, Hu, Frank B., Strickler, Howard D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3425426/
https://www.ncbi.nlm.nih.gov/pubmed/22554827
http://dx.doi.org/10.2337/db11-1488