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Differential Regulation of Smad3 and of the Type II Transforming Growth Factor-β Receptor in Mitosis: Implications for Signaling

The response to transforming growth factor-β (TGF-β) depends on cellular context. This context is changed in mitosis through selective inhibition of vesicle trafficking, reduction in cell volume and the activation of mitotic kinases. We hypothesized that these alterations in cell context may induce...

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Detalles Bibliográficos
Autores principales: Hirschhorn, Tal, Barizilay, Lior, Smorodinsky, Nechama I., Ehrlich, Marcelo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3425481/
https://www.ncbi.nlm.nih.gov/pubmed/22927969
http://dx.doi.org/10.1371/journal.pone.0043459