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Differential Regulation of Smad3 and of the Type II Transforming Growth Factor-β Receptor in Mitosis: Implications for Signaling
The response to transforming growth factor-β (TGF-β) depends on cellular context. This context is changed in mitosis through selective inhibition of vesicle trafficking, reduction in cell volume and the activation of mitotic kinases. We hypothesized that these alterations in cell context may induce...
Autores principales: | Hirschhorn, Tal, Barizilay, Lior, Smorodinsky, Nechama I., Ehrlich, Marcelo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3425481/ https://www.ncbi.nlm.nih.gov/pubmed/22927969 http://dx.doi.org/10.1371/journal.pone.0043459 |
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