Carbon Monoxide Reduces Neuropathic Pain and Spinal Microglial Activation by Inhibiting Nitric Oxide Synthesis in Mice

BACKGROUND: Carbon monoxide (CO) synthesized by heme oxygenase 1 (HO-1) exerts antinociceptive effects during inflammation but its role during neuropathic pain remains unknown. Our objective is to investigate the exact contribution of CO derived from HO-1 in the modulation of neuropathic pain and th...

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Detalles Bibliográficos
Autores principales: Hervera, Arnau, Leánez, Sergi, Negrete, Roger, Motterlini, Roberto, Pol, Olga
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3425507/
https://www.ncbi.nlm.nih.gov/pubmed/22928017
http://dx.doi.org/10.1371/journal.pone.0043693

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3425507/
https://www.ncbi.nlm.nih.gov/pubmed/22928017
http://dx.doi.org/10.1371/journal.pone.0043693

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