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Carbon Monoxide Reduces Neuropathic Pain and Spinal Microglial Activation by Inhibiting Nitric Oxide Synthesis in Mice

BACKGROUND: Carbon monoxide (CO) synthesized by heme oxygenase 1 (HO-1) exerts antinociceptive effects during inflammation but its role during neuropathic pain remains unknown. Our objective is to investigate the exact contribution of CO derived from HO-1 in the modulation of neuropathic pain and th...

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Detalles Bibliográficos
Autores principales:	Hervera, Arnau, Leánez, Sergi, Negrete, Roger, Motterlini, Roberto, Pol, Olga
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3425507/ https://www.ncbi.nlm.nih.gov/pubmed/22928017 http://dx.doi.org/10.1371/journal.pone.0043693

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