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Class IA Phosphatidylinositol 3-Kinase p110α Regulates Phagosome Maturation
Of the various phosphatidylinositol 3- kinases (PI3Ks), only the class III enzyme Vps34 has been shown to regulate phagosome maturation. During studies of phagosome maturation in THP-1 cells deficient in class IA PI3K p110α, we discovered that this PI3K isoform is required for vacuole maturation to...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3425514/ https://www.ncbi.nlm.nih.gov/pubmed/22928013 http://dx.doi.org/10.1371/journal.pone.0043668 |