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An In Silico Study of the Differential Effect of Oxidation on Two Biologically Relevant G-Quadruplexes: Possible Implications in Oncogene Expression

G-quadruplex structures, formed from guanine rich sequences, have previously been shown to be involved in various physiological processes including cancer-related gene expression. Furthermore, G-quadruplexes have been found in several oncogene promoter regions, and have been shown to play a role in...

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Detalles Bibliográficos
Autores principales: Stebbeds, William J. D., Lunec, Joseph, Larcombe, Lee D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3425515/
https://www.ncbi.nlm.nih.gov/pubmed/22928025
http://dx.doi.org/10.1371/journal.pone.0043735