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Tubule-specific ablation of endogenous β-catenin aggravates acute kidney injury in mice

β-catenin is a unique intracellular protein functioning as an integral component of the cell-cell adherens complex and a principal signaling protein mediating canonical Wnt signaling. Little is known about its function in adult kidneys in the normal physiologic state or after acute kidney injury (AK...

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Detalles Bibliográficos
Autores principales: Zhou, Dong, Li, Yingjian, Lin, Lin, Zhou, Lili, Igarashi, Peter, Liu, Youhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3425732/
https://www.ncbi.nlm.nih.gov/pubmed/22622501
http://dx.doi.org/10.1038/ki.2012.173