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Inhaled fluticasone propionate impairs pulmonary clearance of Klebsiella Pneumoniae in mice

BACKGROUND: Recent trials demonstrate increased pneumonia risk in chronic obstructive pulmonary disease patients treated with the inhaled corticosteroid (ICS) fluticasone propionate (FP). There is limited work describing FP effects on host defenses against bacterial pneumonia. METHODS: C57BL/6 mice...

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Detalles Bibliográficos
Autores principales: Patterson, Craig M, Morrison, Richard L, D’Souza, Alain, Teng, Xu S, Happel, Kyle I
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3426464/
https://www.ncbi.nlm.nih.gov/pubmed/22651370
http://dx.doi.org/10.1186/1465-9921-13-40