Protease Cleavage Leads to Formation of Mature Trimer Interface in HIV-1 Capsid

During retrovirus particle maturation, the assembled Gag polyprotein is cleaved by the viral protease into matrix (MA), capsid (CA), and nucleocapsid (NC) proteins. To form the mature viral capsid, CA rearranges, resulting in a lattice composed of hexameric and pentameric CA units. Recent structural...

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Detalles Bibliográficos
Autores principales: Meng, Xin, Zhao, Gongpu, Yufenyuy, Ernest, Ke, Danxia, Ning, Jiying, DeLucia, Maria, Ahn, Jinwoo, Gronenborn, Angela M., Aiken, Christopher, Zhang, Peijun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3426514/
https://www.ncbi.nlm.nih.gov/pubmed/22927821
http://dx.doi.org/10.1371/journal.ppat.1002886

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3426514/
https://www.ncbi.nlm.nih.gov/pubmed/22927821
http://dx.doi.org/10.1371/journal.ppat.1002886

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