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Interleukin-1 Receptor-Associated Kinase 2- and Protein Kinase D1-Dependent Regulation of IRAK-Monocyte Expression by CpG DNA

As a part of the negative feedback mechanism, CpG DNA induces IRAK-M expression in monocytic cells. In the present study we investigated a biochemical signaling pathway and the transcription factors responsible for CpG DNA-mediated Irak-m gene expression. CpG DNA-induced Irak-m expression did not re...

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Detalles Bibliográficos
Autores principales: Kim, Young-In, Park, Jeoung-Eun, Kwon, Ki Han, Hong, Cheol Yi, Yi, Ae-Kyung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3426515/
https://www.ncbi.nlm.nih.gov/pubmed/22928050
http://dx.doi.org/10.1371/journal.pone.0043970