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miR290-5p/292-5p Activate the Immunoglobulin kappa Locus in B Cell Development

Regulated expression of miRNAs influences development in a wide variety of contexts. We report here that miR290-5p (100049710) and miR292-5p (100049711) are induced at the pre-B stage of murine B cell development and that they influence assembly of the Igκ light chain gene (243469) by contributing t...

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Detalles Bibliográficos
Autores principales: Garcia, Patty B., Cai, Amie, Bates, Jamie G., Nolla, Hector, Schlissel, Mark S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3426528/
https://www.ncbi.nlm.nih.gov/pubmed/22928038
http://dx.doi.org/10.1371/journal.pone.0043805