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HGF and Direct Mesenchymal Stem Cells Contact Synergize to Inhibit Hepatic Stellate Cells Activation through TLR4/NF-kB Pathway

AIMS: Bone marrow-derived mesenchymal stem cells (BMSCs) can reduce liver fibrosis. Apart from the paracrine mechanism by which the antifibrotic effects of BMSCs inhibit activated hepatic stellate cells (HSCs), the effects of direct interplay and juxtacrine signaling between the two cell types are p...

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Detalles Bibliográficos
Autores principales: Wang, Pei-pei, Xie, Dong-ying, Liang, Xu-Jing, Peng, Liang, Zhang, Geng-lin, Ye, Yi-nong, Xie, Chan, Gao, Zhi-liang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3426540/
https://www.ncbi.nlm.nih.gov/pubmed/22927965
http://dx.doi.org/10.1371/journal.pone.0043408