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Polysome Profiling in Liver Identifies Dynamic Regulation of Endoplasmic Reticulum Translatome by Obesity and Fasting

Obesity-associated metabolic complications are generally considered to emerge from abnormalities in carbohydrate and lipid metabolism, whereas the status of protein metabolism is not well studied. Here, we performed comparative polysome and associated transcriptional profiling analyses to study the...

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Detalles Bibliográficos
Autores principales: Fu, Suneng, Fan, Jason, Blanco, Joshua, Gimenez-Cassina, Alfredo, Danial, Nika N., Watkins, Steve M., Hotamisligil, Gökhan S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3426552/
https://www.ncbi.nlm.nih.gov/pubmed/22927828
http://dx.doi.org/10.1371/journal.pgen.1002902