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Polysome Profiling in Liver Identifies Dynamic Regulation of Endoplasmic Reticulum Translatome by Obesity and Fasting
Obesity-associated metabolic complications are generally considered to emerge from abnormalities in carbohydrate and lipid metabolism, whereas the status of protein metabolism is not well studied. Here, we performed comparative polysome and associated transcriptional profiling analyses to study the...
Autores principales: | Fu, Suneng, Fan, Jason, Blanco, Joshua, Gimenez-Cassina, Alfredo, Danial, Nika N., Watkins, Steve M., Hotamisligil, Gökhan S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3426552/ https://www.ncbi.nlm.nih.gov/pubmed/22927828 http://dx.doi.org/10.1371/journal.pgen.1002902 |
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