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SLX-1 Is Required for Maintaining Genomic Integrity and Promoting Meiotic Noncrossovers in the Caenorhabditis elegans Germline

Although the SLX4 complex, which includes structure-specific nucleases such as XPF, MUS81, and SLX1, plays important roles in the repair of several kinds of DNA damage, the function of SLX1 in the germline remains unknown. Here we characterized the endonuclease activities of the Caenorhabditis elega...

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Detalles Bibliográficos
Autores principales: Saito, Takamune T., Mohideen, Firaz, Meyer, Katherine, Harper, J. Wade, Colaiácovo, Monica P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3426554/
https://www.ncbi.nlm.nih.gov/pubmed/22927825
http://dx.doi.org/10.1371/journal.pgen.1002888