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SLX-1 Is Required for Maintaining Genomic Integrity and Promoting Meiotic Noncrossovers in the Caenorhabditis elegans Germline
Although the SLX4 complex, which includes structure-specific nucleases such as XPF, MUS81, and SLX1, plays important roles in the repair of several kinds of DNA damage, the function of SLX1 in the germline remains unknown. Here we characterized the endonuclease activities of the Caenorhabditis elega...
Autores principales: | Saito, Takamune T., Mohideen, Firaz, Meyer, Katherine, Harper, J. Wade, Colaiácovo, Monica P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3426554/ https://www.ncbi.nlm.nih.gov/pubmed/22927825 http://dx.doi.org/10.1371/journal.pgen.1002888 |
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