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Allosteric Communication across the Native and Mutated KIT Receptor Tyrosine Kinase
A fundamental goal in cellular signaling is to understand allosteric communication, the process by which signals originated at one site in a protein propagate dependably to affect remote functional sites. Here, we describe the allosteric regulation of the receptor tyrosine kinase KIT. Our analysis e...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3426562/ https://www.ncbi.nlm.nih.gov/pubmed/22927810 http://dx.doi.org/10.1371/journal.pcbi.1002661 |