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Allosteric Communication across the Native and Mutated KIT Receptor Tyrosine Kinase

A fundamental goal in cellular signaling is to understand allosteric communication, the process by which signals originated at one site in a protein propagate dependably to affect remote functional sites. Here, we describe the allosteric regulation of the receptor tyrosine kinase KIT. Our analysis e...

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Detalles Bibliográficos
Autores principales:	Laine, Elodie, Auclair, Christian, Tchertanov, Luba
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3426562/ https://www.ncbi.nlm.nih.gov/pubmed/22927810 http://dx.doi.org/10.1371/journal.pcbi.1002661

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