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Pentamers Not Found in the Universal Proteome Can Enhance Antigen Specific Immune Responses and Adjuvant Vaccines

Certain short peptides do not occur in humans and are rare or non-existent in the universal proteome. Antigens that contain rare amino acid sequences are in general highly immunogenic and may activate different arms of the immune system. We first generated a list of rare, semi-common, and common 5-m...

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Detalles Bibliográficos
Autores principales: Patel, Ami, Dong, Jessica C., Trost, Brett, Richardson, Jason S., Tohme, Sarah, Babiuk, Shawn, Kusalik, Anthony, Kung, Sam K. P., Kobinger, Gary P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3427150/
https://www.ncbi.nlm.nih.gov/pubmed/22937099
http://dx.doi.org/10.1371/journal.pone.0043802