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Pentamers Not Found in the Universal Proteome Can Enhance Antigen Specific Immune Responses and Adjuvant Vaccines
Certain short peptides do not occur in humans and are rare or non-existent in the universal proteome. Antigens that contain rare amino acid sequences are in general highly immunogenic and may activate different arms of the immune system. We first generated a list of rare, semi-common, and common 5-m...
Autores principales: | Patel, Ami, Dong, Jessica C., Trost, Brett, Richardson, Jason S., Tohme, Sarah, Babiuk, Shawn, Kusalik, Anthony, Kung, Sam K. P., Kobinger, Gary P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3427150/ https://www.ncbi.nlm.nih.gov/pubmed/22937099 http://dx.doi.org/10.1371/journal.pone.0043802 |
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