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Circular Permutation Prediction Reveals a Viable Backbone Disconnection for Split Proteins: An Approach in Identifying a New Functional Split Intein

Split-protein systems have emerged as a powerful tool for detecting biomolecular interactions and reporting biological reactions. However, reliable methods for identifying viable split sites are still unavailable. In this study, we demonstrated the feasibility that valid circular permutation (CP) si...

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Detalles Bibliográficos
Autores principales: Lee, Yun-Tzai, Su, Tz-Hsiang, Lo, Wei-Cheng, Lyu, Ping-Chiang, Sue, Shih-Che
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3427171/
https://www.ncbi.nlm.nih.gov/pubmed/22937103
http://dx.doi.org/10.1371/journal.pone.0043820