DIDS Prevents Ischemic Membrane Degradation in Cultured Hippocampal Neurons by Inhibiting Matrix Metalloproteinase Release

During stroke, cells in the infarct core exhibit rapid failure of their permeability barriers, which releases ions and inflammatory molecules that are deleterious to nearby tissue (the penumbra). Plasma membrane degradation is key to penumbral spread and is mediated by matrix metalloproteinases (MMP...

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Detalles Bibliográficos
Autores principales: Pamenter, Matthew E., Ryu, Julie, Hua, Serena T., Perkins, Guy A., Mendiola, Vincent L., Gu, Xiang Q., Ellisman, Mark H., Haddad, Gabriel G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3427179/
https://www.ncbi.nlm.nih.gov/pubmed/22937143
http://dx.doi.org/10.1371/journal.pone.0043995

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3427179/
https://www.ncbi.nlm.nih.gov/pubmed/22937143
http://dx.doi.org/10.1371/journal.pone.0043995

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