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DIDS Prevents Ischemic Membrane Degradation in Cultured Hippocampal Neurons by Inhibiting Matrix Metalloproteinase Release
During stroke, cells in the infarct core exhibit rapid failure of their permeability barriers, which releases ions and inflammatory molecules that are deleterious to nearby tissue (the penumbra). Plasma membrane degradation is key to penumbral spread and is mediated by matrix metalloproteinases (MMP...
Autores principales: | Pamenter, Matthew E., Ryu, Julie, Hua, Serena T., Perkins, Guy A., Mendiola, Vincent L., Gu, Xiang Q., Ellisman, Mark H., Haddad, Gabriel G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3427179/ https://www.ncbi.nlm.nih.gov/pubmed/22937143 http://dx.doi.org/10.1371/journal.pone.0043995 |
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