Specific Genomic Regions Are Differentially Affected by Copy Number Alterations across Distinct Cancer Types, in Aggregated Cytogenetic Data

BACKGROUND: Regional genomic copy number alterations (CNA) are observed in the vast majority of cancers. Besides specifically targeting well-known, canonical oncogenes, CNAs may also play more subtle roles in terms of modulating genetic potential and broad gene expression patterns of developing tumo...

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Detalles Bibliográficos
Autores principales: Kumar, Nitin, Cai, Haoyang, von Mering, Christian, Baudis, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3427184/
https://www.ncbi.nlm.nih.gov/pubmed/22937079
http://dx.doi.org/10.1371/journal.pone.0043689

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3427184/
https://www.ncbi.nlm.nih.gov/pubmed/22937079
http://dx.doi.org/10.1371/journal.pone.0043689

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