Probing the Binding Sites of Antibiotic Drugs Doxorubicin and N-(trifluoroacetyl) Doxorubicin with Human and Bovine Serum Albumins

We located the binding sites of doxorubicin (DOX) and N-(trifluoroacetyl) doxorubicin (FDOX) with bovine serum albumin (BSA) and human serum albumins (HSA) at physiological conditions, using constant protein concentration and various drug contents. FTIR, CD and fluorescence spectroscopic methods as...

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Detalles Bibliográficos
Autores principales: Agudelo, Daniel, Bourassa, Philippe, Bruneau, Julie, Bérubé, Gervais, Asselin, Éric, Tajmir-Riahi, Heidar-Ali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3427208/
https://www.ncbi.nlm.nih.gov/pubmed/22937101
http://dx.doi.org/10.1371/journal.pone.0043814

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3427208/
https://www.ncbi.nlm.nih.gov/pubmed/22937101
http://dx.doi.org/10.1371/journal.pone.0043814

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