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Crystal Structures of Archaemetzincin Reveal a Moldable Substrate-Binding Site
BACKGROUND: Archaemetzincins are metalloproteases occurring in archaea and some mammalia. They are distinct from all the other metzincins by their extended active site consensus sequence HEXXHXXGXXHCX(4)CXMX(17)CXXC featuring four conserved cysteine residues. Very little is known about their biologi...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3427221/ https://www.ncbi.nlm.nih.gov/pubmed/22937112 http://dx.doi.org/10.1371/journal.pone.0043863 |