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Crystal Structures of Archaemetzincin Reveal a Moldable Substrate-Binding Site

BACKGROUND: Archaemetzincins are metalloproteases occurring in archaea and some mammalia. They are distinct from all the other metzincins by their extended active site consensus sequence HEXXHXXGXXHCX(4)CXMX(17)CXXC featuring four conserved cysteine residues. Very little is known about their biologi...

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Detalles Bibliográficos
Autores principales:	Graef, Christine, Schacherl, Magdalena, Waltersperger, Sandro, Baumann, Ulrich
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3427221/ https://www.ncbi.nlm.nih.gov/pubmed/22937112 http://dx.doi.org/10.1371/journal.pone.0043863

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