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Atmospheric Oxygen Tension Slows Myoblast Proliferation via Mitochondrial Activation
BACKGROUND: Mitochondrial activity inhibits proliferation and is required for differentiation of myoblasts. Myoblast proliferation is also inhibited by the ∼20% oxygen level used in standard tissue culture. We hypothesize that mitochondrial activity would be greater at hyperoxia (20% O(2)) relative...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3427224/ https://www.ncbi.nlm.nih.gov/pubmed/22937109 http://dx.doi.org/10.1371/journal.pone.0043853 |