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Histone deacetylase complexes as caretakers of genome stability

Histone deacetylase complexes (HDACs) are powerful regulators of the epigenome. It is now clear that a subset of HDACs also regulate the stability of the genome itself, but not primarily through transcription. Instead, these key HDACs control genome stability more directly by stabilizing enzymes imp...

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Detalles Bibliográficos
Autores principales: Lahue, Robert, Frizzell, Aisling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3427275/
https://www.ncbi.nlm.nih.gov/pubmed/22722985
http://dx.doi.org/10.4161/epi.20922