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Semaphorin-3D and Semaphorin-3E Inhibit the Development of Tumors from Glioblastoma Cells Implanted in the Cortex of the Brain

Class-3 semaphorins are secreted axon guidance factors. Some of these semaphorins have recently been characterized as suppressors of tumor progression. To determine if class-3 semaphorins can be used to inhibit the development of glioblastoma-multiforme tumors, we expressed recombinant sema-3A, 3B,...

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Detalles Bibliográficos
Autores principales: Sabag, Adi D., Bode, Julia, Fink, Dorit, Kigel, Boaz, Kugler, Wilfried, Neufeld, Gera
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3427296/
https://www.ncbi.nlm.nih.gov/pubmed/22936999
http://dx.doi.org/10.1371/journal.pone.0042912