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Is prnt a Pseudogene? Identification of Ram Prt in Testis and Ejaculated Spermatozoa

A hallmark of prion diseases or transmissible spongiform encephalopaties is the conversion of the cellular prion protein (PrP(C)), expressed by the prion gene (prnp), into an abnormally folded isoform (PrP(Sc)) with amyloid-like features that causes scrapie in sheep among other diseases. prnp togeth...

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Detalles Bibliográficos
Autores principales: Pimenta, Jorge, Domingos, Ana, Santos, Pedro, Marques, Carla C., Cantante, Cátia, Santos, Ana, Barbas, João P., Baptista, Maria C., Horta, António E. M., Viegas, Aldino, Mesquita, Patrícia, Gonçalves, João, Fontes, Carlos A., Prates, José A. M., Pereira, Rosa M. L. N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3427297/
https://www.ncbi.nlm.nih.gov/pubmed/22937002
http://dx.doi.org/10.1371/journal.pone.0042957