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Technical and Regulatory Shortcomings of the TaqMan Version 1 HIV Viral Load Assay
BACKGROUND: The lower limit of detection of the original Roche Amplicor HIV plasma viral load (pVL) assay (50 copies/mL) has defined HIV treatment success. The Amplicor assay, however, has been replaced by the Roche TaqMan assay(s). Changes to the limits of detection and calibration have not been va...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3427308/ https://www.ncbi.nlm.nih.gov/pubmed/22937116 http://dx.doi.org/10.1371/journal.pone.0043882 |