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Berberine Reduces Fibronectin Expression by Suppressing the S1P-S1P2 Receptor Pathway in Experimental Diabetic Nephropathy Models

The accumulation of glomerular extracellular matrix (ECM) is one of the critical pathological characteristics of diabetic renal fibrosis. Fibronectin (FN) is an important constituent of ECM. Our previous studies indicate that the activation of the sphingosine kinase 1 (SphK1)-sphingosine 1- phosphat...

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Detalles Bibliográficos
Autores principales: Huang, Kaipeng, Liu, Weihua, Lan, Tian, Xie, Xi, Peng, Jing, Huang, Juan, Wang, Shaogui, Shen, Xiaoyan, Liu, Peiqing, Huang, Heqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3427312/
https://www.ncbi.nlm.nih.gov/pubmed/22937115
http://dx.doi.org/10.1371/journal.pone.0043874