CFTR Regulates Early Pathogenesis of Chronic Obstructive Lung Disease in βENaC-Overexpressing Mice

BACKGROUND: Factors determining the onset and severity of chronic obstructive pulmonary disease remain poorly understood. Previous studies demonstrated that airway surface dehydration in βENaC-overexpressing (βENaC-Tg) mice on a mixed genetic background caused either neonatal mortality or chronic ob...

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Detalles Bibliográficos
Autores principales: Johannesson, Bjarki, Hirtz, Stephanie, Schatterny, Jolanthe, Schultz, Carsten, Mall, Marcus A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3427321/
https://www.ncbi.nlm.nih.gov/pubmed/22937152
http://dx.doi.org/10.1371/journal.pone.0044059

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3427321/
https://www.ncbi.nlm.nih.gov/pubmed/22937152
http://dx.doi.org/10.1371/journal.pone.0044059

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