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Measuring the Maturity of the Fast-Spiking Interneuron Transcriptional Program in Autism, Schizophrenia, and Bipolar Disorder

BACKGROUND: Emerging evidence suggests that fast-spiking (FS) interneurons are disrupted in multiple neuropsychiatric disorders including autism, schizophrenia, and bipolar disorder. FS cells, which are the primary source of synaptic inhibition, are critical for temporally organizing brain activity,...

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Detalles Bibliográficos
Autores principales: Gandal, Michael J., Nesbitt, Addie May, McCurdy, Richard M., Alter, Mark D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3427326/
https://www.ncbi.nlm.nih.gov/pubmed/22936973
http://dx.doi.org/10.1371/journal.pone.0041215