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Rac-Induced Left Ventricular Dilation in Thyroxin-Treated ZmRacD Transgenic Mice: Role of Cardiomyocyte Apoptosis and Myocardial Fibrosis

The pathways inducing the critical transition from compensated hypertrophy to cardiac dilation and failure remain poorly understood. The goal of our study is to determine the role of Rac-induced signaling in this transition process. Our previous results showed that Thyroxin (T4) treatment resulted i...

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Detalles Bibliográficos
Autores principales: Elnakish, Mohammad T., Hassona, Mohamed D. H., Alhaj, Mazin A., Moldovan, Leni, Janssen, Paul M. L., Khan, Mahmood, Hassanain, Hamdy H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3427332/
https://www.ncbi.nlm.nih.gov/pubmed/22936985
http://dx.doi.org/10.1371/journal.pone.0042500