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Human-Specific SNP in Obesity Genes, Adrenergic Receptor Beta2 (ADRB2), Beta3 (ADRB3), and PPAR γ2 (PPARG), during Primate Evolution

Adrenergic-receptor beta2 (ADRB2) and beta3 (ADRB3) are obesity genes that play a key role in the regulation of energy balance by increasing lipolysis and thermogenesis. The Glu27 allele in ADRB2 and the Arg64 allele in ADRB3 are associated with abdominal obesity and early onset of non-insulin-depen...

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Detalles Bibliográficos
Autores principales: Takenaka, Akiko, Nakamura, Shin, Mitsunaga, Fusako, Inoue-Murayama, Miho, Udono, Toshifumi, Suryobroto, Bambang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3427335/
https://www.ncbi.nlm.nih.gov/pubmed/22937051
http://dx.doi.org/10.1371/journal.pone.0043461