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Human-Specific SNP in Obesity Genes, Adrenergic Receptor Beta2 (ADRB2), Beta3 (ADRB3), and PPAR γ2 (PPARG), during Primate Evolution
Adrenergic-receptor beta2 (ADRB2) and beta3 (ADRB3) are obesity genes that play a key role in the regulation of energy balance by increasing lipolysis and thermogenesis. The Glu27 allele in ADRB2 and the Arg64 allele in ADRB3 are associated with abdominal obesity and early onset of non-insulin-depen...
Autores principales: | Takenaka, Akiko, Nakamura, Shin, Mitsunaga, Fusako, Inoue-Murayama, Miho, Udono, Toshifumi, Suryobroto, Bambang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3427335/ https://www.ncbi.nlm.nih.gov/pubmed/22937051 http://dx.doi.org/10.1371/journal.pone.0043461 |
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