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Krüppel-Like Factor 4, a Tumor Suppressor in Hepatocellular Carcinoma Cells Reverts Epithelial Mesenchymal Transition by Suppressing Slug Expression

Krüppel-like factor 4 (KLF4) is a zinc-finger transcription factor that plays an important role in differentiation and pathogenesis. KLF4 has been suggested to act as an oncogene or tumor suppressor in different tumor types. However, the role of KLF4 in hepatocellular carcinoma (HCC) remains unclear...

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Detalles Bibliográficos
Autores principales: Lin, Ze-Shiang, Chu, Hsiao-Chien, Yen, Yi-Chen, Lewis, Brian C., Chen, Ya-Wen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3427336/
https://www.ncbi.nlm.nih.gov/pubmed/22937066
http://dx.doi.org/10.1371/journal.pone.0043593