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Krüppel-Like Factor 4, a Tumor Suppressor in Hepatocellular Carcinoma Cells Reverts Epithelial Mesenchymal Transition by Suppressing Slug Expression
Krüppel-like factor 4 (KLF4) is a zinc-finger transcription factor that plays an important role in differentiation and pathogenesis. KLF4 has been suggested to act as an oncogene or tumor suppressor in different tumor types. However, the role of KLF4 in hepatocellular carcinoma (HCC) remains unclear...
Autores principales: | Lin, Ze-Shiang, Chu, Hsiao-Chien, Yen, Yi-Chen, Lewis, Brian C., Chen, Ya-Wen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3427336/ https://www.ncbi.nlm.nih.gov/pubmed/22937066 http://dx.doi.org/10.1371/journal.pone.0043593 |
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