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Fc Gamma Receptor CD64 Modulates the Inhibitory Activity of Infliximab

BACKGROUND: Tumor necrosis factor (TNF) is an important cytokine in the pathogenesis of inflammatory bowel disease (IBD). Anti-TNF antibodies have been successfully implemented in IBD therapy, however their efficacies differ among IBD patients. Here we investigate the influence of CD64 Fc receptor o...

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Detalles Bibliográficos
Autores principales: Wojtal, Kacper A., Rogler, Gerhard, Scharl, Michael, Biedermann, Luc, Frei, Pascal, Fried, Michael, Weber, Achim, Eloranta, Jyrki J., Kullak-Ublick, Gerd A., Vavricka, Stephan R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3427356/
https://www.ncbi.nlm.nih.gov/pubmed/22937039
http://dx.doi.org/10.1371/journal.pone.0043361