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Activation-induced cytidine deaminase (AID) linking immunity, chronic inflammation, and cancer
Activation-induced cytidine deaminase (AID) is critically involved in class switch recombination and somatic hypermutation of Ig loci resulting in diversification of antibodies repertoire and production of high-affinity antibodies and as such represents a physiological tool to introduce DNA alterati...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer-Verlag
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3427704/ https://www.ncbi.nlm.nih.gov/pubmed/22527246 http://dx.doi.org/10.1007/s00262-012-1255-z |