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A placebo-controlled randomized HPV16 synthetic long-peptide vaccination study in women with high-grade cervical squamous intraepithelial lesions

The aim of this study was to investigate the capacity of an HPV16 E6/E7 synthetic overlapping long-peptide vaccine to stimulate the HPV16-specific T-cell response, to enhance the infiltration of HPV16-specific type 1 T cells into the lesions of patients with HPV16+ high-grade cervical squamous intra...

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Detalles Bibliográficos
Autores principales: de Vos van Steenwijk, Peggy J., Ramwadhdoebe, Tamara H., Löwik, Margriet J. G., van der Minne, Caroline E., Berends-van der Meer, Dorien M. A., Fathers, Lorraine M., Valentijn, A. Rob P. M., Oostendorp, Jaap, Fleuren, Gert Jan, Hellebrekers, Bart W. J., Welters, Marij J. P., van Poelgeest, Mariette I., Melief, Cornelis J. M., Kenter, Gemma G., van der Burg, Sjoerd H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer-Verlag 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3427705/
https://www.ncbi.nlm.nih.gov/pubmed/22684521
http://dx.doi.org/10.1007/s00262-012-1292-7